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Specialty: Cancer & Oncology
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Total 132960 results found since Jan 2013.
Pancreatic adenocarcinoma upregulated factor, a novel endothelial activator, promotes angiogenesis and vascular permeability
in
& S S Koh
Source: Oncogene - August 20, 2012 Category: Cancer & Oncology Authors: S J KimY LeeN Y KimY HwangB HwangJ-K MinS S Koh Tags: PAUF angiogenesis vascular permeability CXCR4 Source Type: research
Matrix protein of vesicular stomatitis virus: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation
g
& Q Li
Source: Cancer Gene Therapy - March 1, 2013 Category: Cancer & Oncology Authors: Y ZhouF WenP ZhangR TangQ Li Tags: vesicular stomatitis virus matrix protein gene therapy vascular endothelial growth factor ascites apoptosis Source Type: research
QTc interval prolongation with vascular endothelial growth factor receptor tyrosine kinase inhibitors
T K Choueiri
Source: British Journal of Cancer AOP - November 6, 2014 Category: Cancer & Oncology Authors: P GhataliaY JeM D KaymakcalanG SonpavdeT K Choueiri Tags: vascular endothelial growth factor receptor tyrosine kinase inhibitors approved QTc interval prolongation meta-analysis cardiac toxicity Source Type: research
Dual targeting of Angiopoetin-2 and VEGF potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours
r & U T Hacker
Source: British Journal of Cancer - February 3, 2015 Category: Cancer & Oncology Authors: O CoutelleL M SchiffmannM LiwschitzM BrunoldV GoedeM HallekH KashkarU T Hacker Tags: Angiopoietin-2 VEGF vascular normalisation basement membrane sleeves xenograft tumours bevacizumab Source Type: research
Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection
& M A Loudon
Source: British Journal of Cancer - July 14, 2015 Category: Cancer & Oncology Authors: C N ParnabyN W ScottG RamsayC MacKayL SamuelG I MurrayM A Loudon Tags: lymph node ratio extramural vascular invasion colon cancer prognosis Source Type: research
Prediction of vascular invasion in hepatocellular carcinoma by next-generation des-r-carboxy prothrombin
toshi Takayama
Source: British Journal of Cancer - January 12, 2016 Category: Cancer & Oncology Authors: Tomoharu KurokawaShintaro YamazakiYusuke MitsukaMasamichi MoriguchiMasahiko SugitaniTadatoshi Takayama Tags: des-r-carboxy prothrombin alpha-fetoprotein vascular invasion hepatocellular carcinoma Source Type: research
Cadherin-5: a biomarker for metastatic breast cancer with optimum efficacy in oestrogen receptor-positive breast cancers with vascular invasion
iam V Dwek
Source: British Journal of Cancer - April 25, 2016 Category: Cancer & Oncology Authors: Simon A FryClaire E RobertsonRuth SwannMiriam V Dwek Tags: breast cancer metastasis biomarker glycosylation cadherin-5 ER positive vascular invasion Source Type: research
A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition
& O Coutelle
Source: British Journal of Cancer - February 27, 2017 Category: Cancer & Oncology Authors: L M Schiffmann M Brunold M Liwschitz V Goede S Loges M Wroblewski A Quaas H Alakus D Stippel C J Bruns M Hallek H Kashkar U T Hacker O Coutelle Tags: angiogenesis cancer microenvironment vascular normalisation extracellular matrix VEGF PDGF Source Type: research
A meta-analysis comparing the risk of metastases in patients with rectal cancer and MRI-detected extramural vascular invasion (mrEMVI) vs mrEMVI-negative cases
amp; Gina Brown
Source: British Journal of Cancer - June 6, 2017 Category: Cancer & Oncology Authors: Muhammed R S Siddiqui Constantinos Simillis Chris Hunter Manish Chand Jemma Bhoday Aurelie Garant Te Vuong Giovanni Artho Shahnawaz Rasheed Paris Tekkis Al-Mutaz Abulafi Gina Brown Tags: extramural vascular invasion MRI rectal cancer Source Type: research
The interplay of matrix metalloproteinase-8, transforming growth factor- β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma
The interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma
British Journal of Cancer 117,
1007 (26 September 2017). doi:10.1038/bjc.2017.249
Authors: Pirjo Åström, Krista Juurikka, Elin S Hadler-Olsen, Gunbjørg Svineng, Nilva K Cervigne, Ricardo D Coletta, Juha Risteli, Joonas H Kauppila, Sini Skarp, Samuel Kuttner, Ana Oteiza, Meeri Sutinen & Tuula Salo
Source: British Journal of Cancer - September 26, 2017 Category: Cancer & Oncology Authors: Pirjo Åström Krista Juurikka Elin S Hadler-Olsen Gunbj ørg Svineng Nilva K Cervigne Ricardo D Coletta Juha Risteli Joonas H Kauppila Sini Skarp Samuel Kuttner Ana Oteiza Meeri Sutinen Tuula Salo Tags: matrix metalloproteinase-8 invasion proteinase web transforming growth factor- β1 vascular endothelial growth factor-C squamous cell carcinoma tongue neoplasms Source Type: research
Pulmonary arterial hypertension in a patient with multiple myeloma during carfilzomib treatment: in search of better management.
CONCLUSION: The mechanism responsible for cardiac and vascular events during carfilzomib therapy is unclear. This case report highlights that it is important to define at baseline the appropriate screening of patients undergoing carfilzomib therapy with specific monitoring and symptom management and that future large prospective controlled studies are needed to define the correct monitoring strategy in refractory and relapsed multiple myeloma and the potential mechanism of vascular events.
PMID: 33525991 [PubMed - as supplied by publisher]
Source: Tumori - February 4, 2021 Category: Cancer & Oncology Tags: Tumori Source Type: research
Risk of nodal disease in patients with MRI-detected extramural vascular invasion in rectal cancer: a systematic review and meta-analysis.
CONCLUSION: The probability of positive lymph nodes in cases of positive mrEMVI is distinctly greater compared with negative cases in rectal cancer. Positive mrEMVI indicates risk of nodal disease prevalence increased by threefold in rectal cancer.
PMID: 33243105 [PubMed - as supplied by publisher]
Source: Tumori - November 29, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research
Signature of the vascular tumor microenvironment as a marker of the therapeutic response to doxorubicin in a preclinical model of osteosarcoma
Am J Cancer Res. 2022 Apr 15;12(4):1843-1854. eCollection 2022.ABSTRACTPredicting a response of osteosarcoma patients to chemotherapy, such as doxorubicin or high-dose methotrexate cocktail, remains a challenge in the clinic. Moreover, the prognostic value of currently used necrosis analysis is debatable. New markers of the therapeutic response or the prognostic response are urgently needed. The microenvironment plays a key role in the vascularization of highly heterogeneous tumors. Using the syngeneic MOS-J mouse model of osteosarcoma, we focused our study on the immunohistochemistry of tumor vascularization in order to i...
Source: Cancer Control - May 9, 2022 Category: Cancer & Oncology Authors: Vincent Crenn J érôme Amiaud Anne Gomez-Brouchet Vincent Potiron Fran çois Gouin Philippe Rosset Louis-Rom ée Le Nail Luciano Vidal Helios Bertin R égis Brion Guillaume Tran Franck Verrecchia Isabelle Corre Fran çoise Redini Source Type: research
Abstract IA24: Tolerability and efficacy of antiangiogenic agents and novel combinations - In search of the optimal therapeutic windows
Antiangiogenic agents are associated with toxicities due to "on-target" effects on neoangiogenesis, vascular dynamics and tissue repair as well as "off-target" side effects in the case of small molecular inhibitors. Nevertheless, the therapeutic window has proven to be adequate for conferring important clinical benefits in a number of advanced tumors. As antiangiogenic therapies became widely used in patient care, progresses have been made in the efforts to identify risk factors of serious adverse reactions and establish guidelines for risk mitigation. Still, therapeutic outcomes with individual agents are limited by the c...
Source: Molecular Cancer Therapeutics - December 6, 2015 Category: Cancer & Oncology Authors: Chen, H. X. Tags: Antiangiogenesis: Safety Issues and Endothelial Metabolism: Oral Presentations - Invited Abstracts Source Type: research
